categoryMenu_new
 
  Home
  EXTRAORDINARY AH Teaching from Spiritual Hierarchy
  AbundantHope
  NEW READERS! Read Here First
  Supporting AH
  Leadership of AbundantHope
  Announcements
  Regional AH Sites
  Other Sites with AH material
  Contact Us
  Becoming A Messiah
  OUR PUBLIC FORUM IS OPEN TOO ALL
  Mission Ideas
  System Busting
  Cleric Letter/English
  Translations of Cleric Letter
  AH Member Writings
  Candace
  Ron
  Rosie
  Jess
  Brian's Poetry
  James
  Giuseppe
  Esteban
  Telepathic Messages
  Candace
  Jess Anthony
  Vince
  Leonette
  John
  Adam
  Bela
  Joyce
  Hazel
  Kibo
  Peter
  Rosie
  Johan
  Lucia
  Lucia G
  Rubens
  Shellee-Kim
  Ben
  Dorothea
  Solon
  Others
  Targeted Messages
  Hano
  Light Flower
  Changing The Face Of Religion
  - Phoenix Journals - PDF in German
  Candace on Religion
  Other Spiritual Pieces
  Spiritual Nuggets by the Masters
  Phoenix Journals
  Phoenix Journals - PDF
  Telepathic Messages PDF books
  Selections from the Urantia Book
  Illustrations For The Urantia Book
  CMGSN Pieces
  THE WAVE
  Environment/Science
  David Crayford and the ITC
 
  Health and Nutrition
  Podcasts, Radio Shows, Video by AH
  Political Information
  True US History
  Human/Animal Rights
  The Miracle That Is Me
  Education
  Resources
  911 Material
  Books - eBooks
  government email/phone #'s
  Self Reliance
  Video
  Websites
  Alternative News Sources
  Art and Music
  Foreign Sites
  Health and Healing
  Human/Animal Rights
  Scientific
  Spiritual
  Vegan Recipes
  Translated Material
  Dutch
  Gekanaliseerde berichten Jess
  Gekanaliseerde berichten Candace
  Gekanaliseerde berichten Anderen
  Artikelen/berichten
  French
  Canal Jess
  Par Candace
  Other Channels
  Articles
  German
  Telepathische Nachrichten (Candace)
  Telepathische Nachrichten (Jess)
  Telepathische Nachrichten (div.)
  AH Mitgliederbeiträge (Candace)
  AH Mitgliederbeiträge (Jess)
  Spirituelle Schätze
  Italian
  Translations - Candace
  Translations - Jess
  Translations - Others
  Portuguese
  by Candace
  By Jess
  By Others
  Spanish
  Anfitriones Divinos
  Bitácoras Fénix
  Creadores-de-Alas (WingMakers/Lyricus)
  Escritos de Candace
  Escritos de Otros
  Monjoronsón
  Telemensajes de Candace
  Telemensajes de Jess Anthony
  Telemensajes de Otros
  Chinese
  By Candace
  By Jess
  By Others
  Korean Translations
  Hungarian Translations
  Swedish Translations

Search
[an error occurred while processing this directive]
Health and Nutrition Last Updated: Aug 5, 2020 - 7:21:33 AM


We’ve Spent a TRILLION Dollars on Statins to Lower Cholesterol, yet cardiovascular deaths have gone UP – it’s achieved nothing
By Dr. Malcolm Kendrick
Aug 5, 2020 - 1:32:13 AM

Email this article
 Printer friendly page Share/Bookmark

https://www.rt.com/op-ed/497065-cholesterol-statins-cardiovascular-disease/


4 Aug, 2020
Get short URL

We've spent a TRILLION dollars on statins to lower cholesterol, yet cardiovascular deaths have gone UP - it's achieved nothing

FILE PHOTO. ©  Getty Images / Erik Jonsson / EyeEm

By Malcolm Kendrick, doctor and author who works as a GP in the National Health Service in England. His blog can be read here and his book, 'Doctoring Data - How to Sort Out Medical Advice from Medical Nonsense,' is available here.

New research shows that the most widely prescribed type of drug in the history of medicine is a waste of money. One major study found that the more ‘bad' cholesterol was lowered, the greater the risk of heart attacks and strokes.

In the midst of the Covid-19 pandemic, almost every other medical condition has been shoved onto the sidelines. However, in the UK last year, heart attacks and strokes (CVD) killed well over 100,000 people - which is at least twice as many as have died from Covid-19.

CVD will kill just as many this year, which makes it significantly more important than Covid-19, even if no one is paying much attention to it right now. So, it is good to see that research goes on, and papers are still being published.

One of the most significant, and of great interest to me personally, was a critical examination of the benefits of lowering cholesterol. This was published on August 4. The paper was called ‘Hit or miss: the new cholesterol targets,' and it came out in Evidence Based Medicine, one of the key titles that sits under the umbrella of British Medical Journal publishing.

READ MORE Fat chance! Nannying BoJo's plans to get Britain eating healthily and exercising are doomed to failure

Fat chance! Nannying BoJo's plans to get Britain eating healthily and exercising are doomed to failure

It was carefully worded, as all clinical papers are, but a key section of the press release was as follows: "Setting targets for ‘bad' (LDL) cholesterol levels to ward off heart disease and death in those at risk might seem intuitive, but decades of research have failed to show any consistent benefit for this approach, reveals an analysis of the available data, published online in BMJ Evidence Based Medicine."

What is being said here is the following. Everyone thinks that lowering LDL, aka ‘bad cholesterol,' is considered the single most important way to reduce the risk of heart disease and strokes. However, "decades of research have failed to show any consistent benefit for this approach."

Surely this flies in the face of almost all the advice we have been bombarded with for the last 50 years or so. Cholesterol - by which we really mean low density lipoprotein (LDL) - is a killer and must be lowered. This is the whole point of statins, the single most widely prescribed type of drug in the history of medicine. Drugs that have racked up sales of nearly $1 trillion since their launch.

Now, newer and far more expensive LDL-lowering medications are available, riding on the success of statins. They are injectable, rather than tablets, and the cost is far higher. In the US, you are looking at around $5,000 per year. In the UK, one of these drugs, Repatha, costs the NHS just over £4,000 ($5,200) per year. These drugs are known as PCSK9-inhibitors.

These are eye-watering costs. It is estimated that around seven million people in the UK take statins currently. If everyone converted to a PCSK9-inhibitor, this would cost the NHS £28 billion ($36.4 billion) a year - not far off the entire defense budget.

READ MORE Make no mistake: Burger King's vaunted ‘real food' burger without additives will still KILL YOU

Make no mistake: Burger King's vaunted ‘real food' burger without additives will still KILL YOU

But do these drugs work, does lowering LDL work? Surely it does, surely it must. The answer is, not necessarily. Yes, statins have been found to reduce the risk of cardiovascular disease, not by a massive amount, but the effect exists. At least in some studies, if not all.

However, many other drugs also reduce the risk of cardiovascular disease without having any effect on LDL levels, e.g. aspirin. A number of researchers have long argued that the benefits of statins are mainly due to "off-target" effects, by which they mean that, yes, statins lower LDL, but they also have effects on many other things and it is the "other things" that provide the benefit.

For example, statins have been found to have quite strong anti-coagulant (anti-blood-clotting) effects. Same as aspirin, as highlighted in the 2013 paper, ‘Anticoagulant effects of statins and their clinical implications.' It states: "There is evidence indicating that statins... may produce several cholesterol-independent antithrombotic [anti-coagulant] effects."

So, it has always remained possible that the main benefit of statins was not due to their impact on lowering LDL. It is because of something else that they do.

In this recent study, the authors decided to examine this possibility. So they gathered together all the LDL lowering trials - at least those big enough, and long enough to count - and try to establish whether the amount that the LDL was lowered matched the reduction, if any, in cardiovascular disease. The technical term for this is "dose-response."

Or, to put this another way, if the LDL hypothesis is correct, the greater the LDL lowering, the greater the benefit on CVD should be. What did they find? Here are the key findings - from the press release:

"Their analysis showed that over three quarters of all the trials reported no positive impact on the risk of death and nearly half reported no positive impact on risk of future cardiovascular disease.

"And the amount of LDL cholesterol reduction achieved didn't correspond to the size of the resulting benefits, with even very small changes in LDL cholesterol sometimes associated with larger reductions in risk of death or cardiovascular ‘events,' and vice versa.

"Thirteen of the clinical trials met the LDL cholesterol reduction target, but only one reported a positive impact on risk of death...

"Considering that dozens of [randomized controlled trials] of LDL-cholesterol reduction have failed to demonstrate a consistent benefit, we should question the validity of this theory."

And they conclude: "In most fields of science the existence of contradictory evidence usually leads to a paradigm shift or modification of the theory in question, but in this case the contradictory evidence has been largely ignored, simply because it doesn't fit the prevailing paradigm."

ALSO ON RT.COMWith Brits now officially fatter than PIGS, it's time for BoJo to grab UK's killer obesity crisis by the love handles

In short, what they found was that there was absolutely no correlation between the amount that LDL was lowered and the resulting benefit on CVD. In fact, the benefit was inverse i.e. the less the LDL was lowered, the greater the benefit.

This is a hugely important finding that really ought to be shouted from the rooftops. I admit I have a horse in the race, having long argued that LDL has nothing to do with heart disease (and being roundly condemned for doing so). So, it is nice to have my thoughts so powerfully supported in a peer-reviewed, high-impact journal.

For the average person on the street, what this research means is that you should stop worrying about your LDL levels, and obsessively trying to get them down with drugs or diet. Tucked away in the paper was this significant finding:

"Moreover, consider that the Minnesota Coronary Experiment, a four-year long RCT [randomized controlled trial] of a low-fat diet involving 9,423 subjects, actually reported an increase in mortality and cardiovascular events despite a 13 percent reduction in total cholesterol."

Cholesterol (LDL) went down, CVD went up. We really are wasting a colossal amount of money.

[Colour fonts and bolding added.].

The statements, views and opinions expressed in this column are solely those of the author and do not necessarily represent those of RT.




All writings by members of AbundantHope are copyrighted by
©2005-2020 AbundantHope - All rights reserved

Detailed explanation of AbundantHope's Copyrights are found here


Top of Page

Health and Nutrition
Latest Headlines
Daniel Andrews thinks 'accountability menas he keeps his job'
New Study Shows Honeybee Venom ‘Rapidly Destroys’ Some Cancer Cells
Is a New Wave of Covid-Fascism Invading Europe?
Harken, The Covidean Creed...
The Vaccine Hoax is Over. Documents From UK Reveal 30 Years of Cover-up
US Military Suicides Soar as Service Members Struggle Under Covid, war-zone Deployments, National Disasters & Civil Unrest
6 Months MORE of Lockdown, a Possible 'third wave' of Coronavirus, By Then a Vaccine May Be Ready, government advisor warns
Navy Invention Detects Feverish People in Crowds Up to 200 Yards Away, Available for Licensing
New Research Explains Why Children Are Far Less Vulnerable To COVID-19 Than Adults
A Global Medical Tyranny: Vaccines are Destroying the Genetic Fabric of Society
The Supply Chain Is Broken And Food Shortages Are Here
German Minister Admits Lockdown Will Kill More Than COVID-19 Does
Freedom Starts by Not Wearing a Mask
CDC Data Shows High Virus Survival Rate: 99%-Plus for Ages 69 and Younger, 94.6% for Older
Former NY Times Journalist Tells Tucker Carlson Real Purpose of Masks in COVID Crisis
COVID Vaccine Clinical Trials Doomed to Fail; Fatal Design Flaw; NY Times opinion piece exposes all three major clinical trials
How Women Elevate Men To A Higher Purpose
Victoria’s Creeping Totalitarianism is Based On Wild Overreaction to Covid, and the Rest of the World is Going Down the Same Path
Sweden Dominates Drug-Deaths In Europe
Women Are Not OK